At the expense of rare songs? Yes, there is. Hell, I've only seen Rush twice and I'll take the rare stuff over the hits. The hits are great but I've always been a deep cuts person. Keeps things more interesting, especially once you've seen a band a lot.
It should be noted that I fucking love Middletown Dreams though. I've been addicted to it since I got Power Windows.
12/16 - Queens of the Stone Age